Production

with three multiproduct gmp facilities we very flexibly meet your needs

flexibility makes the difference

Our three multiproduct GMP facilities are run by highly motivated and experienced teams. A proven technology transfer approach lets us smoothly adopt and implement processes from our clients or our own process development department.

We regularly and successfully use defined procedures to scale production up and down as required. To ensure efficient, transparent work, we apply professional project management methods based on international standards. Our large equipment fleet and extensive experience with many product types (including recombinant proteins, antibody fragments, pDNA, and vaccines) enable us to very flexibly meet your needs.

We regularly and successfully use defined procedures to scale production up and down as required. To ensure efficient, transparent work, we apply professional project management methods based on international standards. Our large equipment fleet and extensive experience with many product types (including recombinant proteins, antibody fragments, pDNA, and vaccines) enable us to very flexibly meet your needs.

drug substance manufacturing

Richter BioLogics operates three multipurpose facilities for manufacturing biological drug substances with microbial expression systems.

PRODUCT CLASSES

The product types manufactured with microbial expression systems at Richter BioLogics include recombinant proteins and peptides, plasmid DNA, and bacterial vaccines.

Plasmid DNA 

We offer a proprietary, high-performance pDNA process: RB-pART, that efficiently delivers pDNA product in terms of yields and timelines and is fully scalable from 10–1,500 L.

Protein

Protein manufacturing services from development to release of finished product including project management and regulatory support – Richter BioLogics is your trusted CDMO partner for production of late and commercial products.

GMP

Relevant good manufacturing practices are applied to all manufacturing activities at Richter BioLogics.

Frequently Asked Questions

What production systems does Richter BioLogics use?

Richter BioLogics specializes in E. coli, P. pastoris, and cell-free (CFPS) systems, and supports additional microbial strains upon request.

Our core competencies include manufacturing of a wide range of biologics, such as:

  • Nanobody/VHH
  • Therapeutic proteins and peptides
  • Bacterial Vaccines
  • Plasmid DNA (pDNA)

We also produce proteins in a cell-free protein synthesis (CFPS) system.

Richter BioLogics offers fermentation capacities from 10L to 1,500L, supported by cutting-edge equipment. Our production sites offer capacities of:

  • 2 x 300L fermenters
  • 2 x 1,500L fermenters
  • 100% oxygen aeration technology for high-yield fermentation
  • MeOH feed

We produce materials a variety of quality grades, including:

  • Non-GMP
  • High-Quality
  • Critical Raw Material (CRM)
  • GMP-compliant